The COX6A1 antibody from MyBioSource.com is a Mouse Monoclonal antibody to COX6A, and COX6A1. This antibody recognizes Human antigen. The COX6A1 antibody has been validated for the following applications: Flow Cytometry, and Immunofluorescence.
Description
Mouse monoclonal COX6A1 antibody
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transferfrom reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded bymitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunitsfunction in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of thecomplex. COX6A1 encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity